Scientists have uncovered an unexpected way cells can generate cancer-driving proteins—by cutting RNA into shorter, ...

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EXPLAIN ALL THIS. MINDY, WE’VE BEEN HEARING A LOT ABOUT THESE VACCINES OVER THE PAST FIVE, SIX YEARS, RIGHT? KAI RNA VACCINES GAINED A LOT OF ATTENTION DURING THE HEIGHT OF THE COVID 19 PANDEMIC. THE ...

Penn Engineers have redesigned a key component of lipid nanoparticles (LNPs), the delivery vehicles behind mRNA vaccines, to steer the particles toward lymph nodes while reducing off-target delivery ...

Scientists are making rapid progress toward a long-awaited goal that could help to reshape cancer care: mRNA cancer vaccines with the potential to significantly boost the immune system’s ability to ...

Researchers have found that targeted delivery of messenger RNA (mRNA) can restore sperm production and fertility in genetically infertile male mice. The findings, published in Stem Cell Reports, ...

The Food and Drug Administration rejected Moderna’s application for its mRNA-based flu vaccine, the drugmaker said Tuesday. Subscribe to read this story ad-free Get unlimited access to ad-free ...

Double-stranded RNA (dsRNA) is a critical immunostimulatory impurity in mRNA production and poses a problem for the downstream purification methods vital to manufacturing mRNA vaccines and ...

In a small clinical trial, customized mRNA vaccines against high-risk skin cancers appeared to reduce the risk of cancer recurrence and death by nearly 50 percent over five years when compared with ...

Pfizer's mRNA flu vaccine worked better than a standard flu shot in a large Phase 3 trial, researchers reported. The results, published Nov. 19 in The New England Journal of Medicine, suggest that ...