Epidemiology links AA and atopy: up to 40% of AA patients have atopic comorbidities, and concurrent AD predicts poorer response and relapse. Immune profiling shows mixed Th1/Th2/Th22 activation with ...

Spatial and single-cell analyses of human donor pancreata showed that PanIN epithelial cells gradually acquire cancer-like molecular features, while their surrounding stromal and immune environment ...

Exploring the differentiation of iPSC to trunk tenocytes and how the single-cell RNA sequencing and pathway analysis can assist in making it more specific.

A novel spatial transcriptomics atlas developed by Northwestern Medicine scientists may improve the understanding of niche cellular interactions in the gastrointestinal tract that promote the ...

With global life expectancy steadily increasing, the growing gap between lifespan and healthspan has placed the aging of the ...

Transcriptomics of two prevailing models, cuprizone (CPZ) and lysophosphatidylcholine (LPC), reveal understanding of myelin loss and regeneration.

A new study may pave the way toward more personalized treatments for patients with high-risk bladder cancer, according to a study published in European Urology.

Multidimensional analyses demonstrate that repeated DeltEx DRI dosing preserves immune function, drives tumor microenvironment remodeling, and correlates with improved survival ou ...

Nick is a freelance writer from Chicago, IL, with a BA in Creative Writing from the University of Illinois at Urbana-Champaign. His lifelong belief in the artistic power of video games led him to ...

The Phase 1 study of RLS-1496, the first human trial of a GPX4 (selective glutathione peroxidase 4) modulator, met its primary endpoint and also demonstrated a statistically significant relationship ...

Do you want to generate spatial transcriptomics data using your H&E images? We introduce DeepSpot, a novel deep-learning model that predicts spatial transcriptomics from H&E images. DeepSpot employs a ...

Background Intraductal papillary mucinous neoplasms (IPMNs) are precursor lesions of pancreatic cancer with highly variable malignant potential. Current understanding of their biology remains ...