AI for molecular simulations may not need built-in physics to deliver strong results

Simulating how atoms and molecules move over time is a central challenge in computational chemistry and materials science.

Candidate breast cancer drug overloads tumors with 'surge' of toxic lipids

An experimental drug targeting triple-negative breast cancer overwhelms cancer cells with toxic fats, according to new tests ...
eLife

Revealing global stoichiometry conservation architecture in cells from Raman spectral patterns

Conservation levels of gene expression abundance ratios are globally coordinated in cells, and cellular state changes under such biologically relevant stoichiometric constraints are readable as ...
Morning Overview on MSN

UV-exposed water creates hydroxyl radicals via unexpected reaction path

Water treatment plants across the globe rely on ultraviolet light to generate hydroxyl radicals, the aggressive molecular ...
technologynetworks

Ultra-Robust Machine-Learning Model Can Simulate Molecules at Extreme Temperatures

The study, published in Communications Chemistry, explores the first AI‑powered model that can keep molecular simulations running safely and smoothly, even when molecules are pushed to extreme ...
technologynetworks

Machine-Learning Model Enables Ultra-Stable Molecular Simulations at Extreme Temperatures

Researchers at The University of Manchester have created a groundbreaking physics‑informed machine‑learning model that can run molecular simulations for unprecedented lengths of time, even at ...
Phys.org

Ultra‑robust machine‑learning models run stable molecular simulations at extreme temperatures

Researchers at The University of Manchester have created a physics‑informed machine‑learning model that can run molecular simulations for unprecedented lengths of time, even at temperatures as high as ...
ascopubs.org

Molecular-Based Ecosystem to Improve Personalized Medicine in Chronic Myelomonocytic Leukemia

Phase I Study of Mosperafenib, a Novel Paradox Breaker B-Raf Proto-Oncogene Serine/Threonine Kinase (BRAF) Inhibitor, in Patients With BRAF V600-Mutant Solid Tumors Chronic myelomonocytic leukemia ...
Morningstar

Oral Small Molecule Amylin Receptor Agonist ASC39 Demonstrated Eloralintide-like Amylin Selectivity and Efficacy in Preclinical Models

- In a head-to-head cyclic adenosine monophosphate (cAMP) activation assay vs. eloralintide, oral small molecule amylin receptor agonist ASC39 demonstrated similar selectivity and potency to that of ...
ascopubs.org

Foundation Model Based on Routine Magnetic Resonance Imaging for Brain Tumor Molecular Profiling and Progression Prediction

To build a self-supervised magnetic resonance imaging (MRI) foundation model from routine clinical scans and to test whether it can support key glioma-related applications, including post-therapy ...
The New York Times

Researchers Are Using A.I. to Decode the Human Genome

AlphaGenome is a leap forward in the ability to study the human blueprint. But the fine workings of our DNA are still largely a mystery. By Carl Zimmer In 2024, two scientists from Google DeepMind ...