From raw DNA sequences to meaningful biological insights, genome annotation and visualization tools are transforming how scientists interpret genetics. By combining genome browsers, annotation ...

(TP53), widely known as the “guardian of the genome,” is one of the most frequently altered genes in human cancer. While its canonical tumor-suppressive ...

Single-cell analysis is reshaping drug discovery, but interpretation remains slow. AI single cell approaches may close the ...

Researchers have developed the IFAM model, which integrates diverse functional genomic annotations to enhance prediction accuracy for complex traits. Tested on datasets from humans, livestock, and ...

Recent work in 3D scene understanding is moving beyond purely spatial analysis toward functional scene understanding. However, existing methods often consider functional relationships between object ...

Background The gut-liver axis plays a critical role in liver disease progression; however, how gut microbial ecology and function vary across disease stages remains unclear. Objective To define ...

This important study presents a methodologically rigorous framework for stability-guided fine-mapping, extending PICS and generalizing to methods such as SuSiE, supported by comprehensive simulations ...

Abstract: Dexterous grasp datasets are vital for embodied intelligence, but mostly emphasize grasp stability, ignoring functional grasps needed for tasks like opening bottle caps or holding cup ...

In this issue of PNAS, Cao et al. (6) extend these applications to detect the molecular underpinnings of phenotypic convergence by decoding patterns invisible to traditional sequence analysis ...

Antimicrobial resistance (AMR) is a growing health challenge, reducing the effectiveness of life-saving treatments and increasing the risk of complications from routine medical procedures. To support ...