In the largest and longest trial of its kind, 90% of patients receiving an experimental gene therapy for congenital deafness ...

Everyday DNA mutations can help us understand immune function and aging—and even mitigate harm caused by some inherited ...

Humans have about 3 billion DNA bases in their genetic makeup. However, most of it does not encode for protein.

The ability of different genetic variants—changes to one or more building blocks of DNA—to cause disease, and to what extent, has historically been opaque. Geneticist and Crick group leader Greg ...

Weiwei Fan (left) and Ronald Evans (right) developed a new platform for studying mitochondrial DNA mutations that lights the way to new therapeutics for mitochondrial diseases and mitochondrial ...

University of Virginia School of Medicine researchers have used an advanced gene-editing technique to correct the underlying cause of a severe form of epilepsy in lab mice. This breakthrough could one ...

GRAND RAPIDS, Mich — There is a rare gene mutation linked to sudden cardiac death and heart failure called phospholamban (PLN). It may not be very common worldwide, but likely more so in West Michigan ...

Clones had mutations triple the rate of normal mice By the 58th generation, clones died within days of birth 1,206 cloned mice were generated from 2005 to 2025 Clones pass all their defective genes to ...

GRAND RAPIDS, Mich. (WOOD) — The Michigan State University College of Human Medicine is working to raise awareness of an often hidden gene mutation that’s linked to Dutch ancestry. The PLN gene acts ...

One of the symptoms of schizophrenia is difficulty incorporating new information about the world. This can lead patients to struggle with making decisions and, eventually, to lose touch with reality.

Scientists have identified a genetic mutation that helps protect the brain function of animals that live in high-altitude, low-oxygen environments. This mutation has provided new insights into how ...

Researchers at Cardiff University have uncovered how a particularly severe form of DNA damage arises—shedding new light on mutation processes that contribute to cancer and inherited genetic conditions ...