The advent of single-cell omics technologies has revolutionized our understanding of the complex cellular landscape in cancer. Traditional bulk sequencing ...
Understanding which cells within a tumor will go on to form metastases remains one of the major challenges in cancer research ...
Target identification is a critical and challenging step in drug discovery, with only a small fraction of human genes ...
In the past decade, immune checkpoint inhibitors (ICIs) have dramatically changed cancer treatment, significantly improving ...
Resistant and severe hypertension represent a growing global health burden and are associated with a markedly increased risk of cardiovascular, renal, and ...
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment but can cause immune‑mediated hepatotoxicity (IMH), a potentially serious ...
Spatial transcriptomics is revolutionizing the study of tissue architecture, cellular states, and tumor-immune interactions in clinical specimens. This presentation introduces the principles and ...
A robust and quantitative map links chromatin modification and gene expression of cells during zebrafish embryogenesis.
As far as research subjects go, it's not always easy to find common ground with a single-celled bacterium. Yet the more Paul ...
A study identifies tumor cells with metastatic potential within primary tumors, showing Prrx1 gene levels control invasion, ...