eLife

Molidustat Targets a Synthetic Lethal Vulnerability in APC-Mutant Colorectal Cancer through GSTP1 and PHD2 Co-Inhibition

This important paper substantially advances our understanding of how Molidustat may work, beyond its canonical role, by identifying its therapeutic targets in cancer. This study presents a compelling ...

Celebrity birthdays for the week of May 3-9 includes Jackie Jackson and Cheryl Burke

Celebrities having birthdays during the week of May 3-9 include singer Jackie Jackson of The Jacksons, “Boardwalk Empire” ...
Beirut Time

Mapping convergent regulators of melanoma drug resistance by PerturbFate

A375, HEK293T, Sk-Mel-3 and Sk-Mel-24 cell lines were obtained from the American Type Culture Collection. A375 and HEK293T cells were maintained in ...
Smithsonian Magazine

Could Python Blood Lead to the Next Generation of Weight-Loss Drugs?

Burmese pythons have pretty irregular eating habits. One of these giant reptiles can swallow an entire antelope whole and then go up to a year and a half without additional meals. Now, scientists have ...
Hosted on MSN

Matrix Awakens PC: HDD vs SSD M.2

Matrix Awakens : 1TB hdd vs 1TB ssd M.2 l 1440p System: Windows 10 Ryzen 9 5900X asus rog X570 Crosshair viii Hero 32Gb ram DDR4 3800Mhz cpu Cooler - msi mag coreliquid C360 GeForce rtx 3080 10GB ssd ...
eLife

Reassessing prediction in the brain: Pre-onset neural encoding during natural listening does not reflect pre-activation

This study presents valuable findings by reanalyzing previously published MEG and ECoG datasets to challenge the predictive nature of pre-onset neural encoding effects. The evidence supporting the ...
Nature

Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus

Mechanical forces influence the growth and shape of virtually every tissue and organ in our bodies. However, little is known about the mechanisms by which individual cells sense these mechanical ...