eLife

Serotonergic modulation of motor subspace dynamics drives a sleep-independent quiescent state

The dorsal raphe nucleus (DRN) serotonergic (5-HT) system has been implicated in regulating sleep and motor control; however, its specific role remains controversial. In this study, we found that ...
eLife

Speech is defined by theta-gamma coupled acoustic rhythms, mapped onto segregated populations in human early auditory cortex

This manuscript presents important findings that challenge traditional models of speech processing by demonstrating that theta-gamma phase-amplitude coupling in the auditory cortex is primarily a ...
Nature

Paradoxical inhibition of T-cell function in response to CTLA-4 blockade; heterogeneity within the human T-cell population

We developed an assay of T cell activation involving stimulation of highly purified CD4 + T cells with immobilized antibodies against CD3/CD28, in the presence or absence of blocking monomeric Fab ...