Scientists reveal a hidden second layer of human DNA, showing how genome folding controls genes and influences disease development.

(L to R) Co-first author Jackson Mobley, PhD, corresponding author Daniel Savic, PhD, and co-first author Kashi Raj Bhattarai, PhD, all of the St. Jude Department of Pharmacy and Pharmaceutical ...

Researchers have revealed that so-called ‘junk DNA’ contains powerful switches that help control brain cells linked to Alzheimer’s disease. When people picture DNA, they often imagine a set of genes ...

Following a double-strand DNA break, an enzyme called PARP1 helps hold the two strands together —like superglue— and creates a safe zone for other proteins to come repair the damage. We don’t exactly ...