Brain cells (magenta) in the reward center of a rat’s brain release dopamine in response to opioids. According to a new study by WashU Medicine researchers, male and female rats with a chronic pain ...

Combating the opioid crisis relies on identifying new prevention strategies for problematic fentanyl use. In a collaboration ...

Can a better environment stop opioid relapse? Environmental enrichment lowers stress hormones and reduces fentanyl seeking in ...

Last week, researchers dropped a bombshell report on DFNZ, a developing new medicine derived from a class of drugs once ...

While the opioid epidemic is one of the most urgent public health emergencies facing the U.S., new therapeutic approaches for ...

While opioids are incredibly powerful pain management tools, they can also be highly addictive. Since 2013, the rate of deaths from an overdose due to synthetic opioids, like fentanyl, has steadily ...

Could sex hormones explain the difference in opioid use and misuse between genders? Since 1999, the American opioid epidemic has killed more than half a million people, and according to the National ...

Is there a safe opioid? Scientists discovered DFNZ, a high-potency nitazene that relieves pain without the risk of overdose ...

More good news in the battle against opioid addiction. Scientists have reopened research into a class of opioids that were ...

Opioids show variable efficacy for acute pain management across clinical settings and timepoints, with some increasing risk for adverse events.