The transcription factor p53 is the most frequently inactivated tumour suppressor in cancer. Approaches to restore its wild-type function are challenging and have not led to approved drugs. An ...
The tumor suppressor protein p53 plays a critical role in preventing cancer by regulating cell cycle, apoptosis, and genomic stability. However, mutations in the P53 gene are found in over 50% of ...
A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the tumor suppressor p53 gene—found very frequently in human tumors—hijack DNA ...
Results that may be inaccessible to you are currently showing.
Hide inaccessible results