In a landmark effort to understand how the physical structure of our DNA influences human biology, Northwestern investigators and the 4D Nucleome Project have unveiled the most detailed maps to date ...
An illustration of multicolored tangle of threads within a small black sphere. A 3D illustration shows DNA packaged into the nucleus, scientists with the 4D Nucleome project are now building accurate ...
KO imaging screens reveal that disruption of mitotic processes impairs spatial genome organization in daughter cells.
Scientists have uncovered a surprising secret about our DNA: it’s not a static blueprint, but a constantly shifting, folding structure that helps control how genes turn on and off. Researchers at the ...
The 55th Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Research has been awarded to professor Steven Henikoff of Fred Hutch Cancer Center in Seattle, Washington, for his work on ...
CRISPR Cas9 genome editing has transformed the way scientists approach gene therapy, acting like precise DNA scissors that can target and repair hereditary diseases at the genetic level. This ...
The history of genomics has long been a story of reading a book where only every fiftieth page made sense. While the Human Genome Project gave us the full sequence of human DNA over two decades ago, ...
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In a monumental scientific effort, the human genome has been mapped across time and space in four dimensions
The Human Genome Project was completed a little over twenty years ago. Now, scientists involved in the 4D Nucleome Project have created a detailed map that not only showcases the human genome in 3D, ...
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